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Denali Therapeutics Inc. Share Price

Denali Therapeutics Inc. Share Price

NASDAQ: DNLI | Mid Cap
$24.31
-$0.05 (-0.18%) Last updated on 19 Aug, 2026 | 01:29 IST
  • Performance
  • Chart
  • Fundamentals
  • Quarterly P&L
  • Annual P&L
  • About
  • Price history
  • FAQs

Denali Therapeutics Inc. Stock Performance

Open
$24.32
Prev. Close
$24.36
Circuit Range
N/A
Day Range
$24.01 - $24.48
Year Range
$12.61 - $27.27
Volume
64,146
Average Traded
$24.22

Denali Therapeutics Inc. Share Price Today

As of 19 August 2026, Denali Therapeutics Inc.'s share price is $24.31. The stock opened at $24.32, compared to its previous close of $24.36. During today's trading session, Denali Therapeutics Inc.'s share price traded between $24.01 and $24.48, with an average price of $24.24. Over the past 52 weeks, the stock has recorded a high of $27.27 and a low of $12.61. In terms of performance, Denali Therapeutics Inc.'s share price has risen by 14.75% over the last six months and is up 58.99% on a year-on-year basis.

Denali Therapeutics Inc. Share Price Chart

$24.01$24.48
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Denali Therapeutics Inc. Stock Fundamentals & Key Indicators

Market Cap
$4.20B
PE Ratio (TTM)
-8.19
Dividend Yield
N/A
EPS (TTM)
$-2.97
Revenue (TTM)
N/A
Return On Equity (TTM)
-50.56%
Profit Margin
N/A
Debt to Equity
0.10
Quarterly Earnings Growth YoY
N/A

Denali Therapeutics Inc. Quarterly Profit & Loss

All figures in USD

ParticularsMar 2024Jun 2024Sep 2024
Revenue$0.00$0.00$0.00
Net Profit-$101.80M-$99.03M-$107.19M
Net Profit MarginN/AN/AN/A
Income ChangeN/A2.73%-8.25%

Denali Therapeutics Inc. Annual Profit & Loss

All figures in USD

Particulars20212022202320242025
Revenue$48.66M$108.46M$330.53M$0.00$0.00
Net Profit-$290.58M-$325.99M-$145.22M-$422.77M-$512.54M
Net Profit Margin-597.15%-300.56%-43.94%N/AN/A
Income ChangeN/A-12.19%55.45%-191.12%-21.23%

About Denali Therapeutics Inc.

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Denali Therapeutics Inc. Historical Returns

MonthOpenCloseChange %
Aug 2026
$22.80
$24.36
+5.85%
Jul 2026
$25.83
$23.01
-10.54%
Jun 2026
$20.86
$25.72
+22.30%
May 2026
$18.53
$21.03
+12.46%
Apr 2026
$19.57
$18.70
-2.50%
Mar 2026
$21.07
$19.18
-9.46%
Feb 2026
$21.27
$21.18
-2.69%
Jan 2026
$16.57
$21.77
+31.86%
Dec 2025
$19.13
$16.51
-15.20%
Nov 2025
$16.12
$19.47
+19.59%
Oct 2025
$15.03
$16.28
+12.08%
Sep 2025
$15.10
$14.53
-5.00%

DNLI Share Price FAQs

What is Denali Therapeutics Inc. share price today?

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Denali Therapeutics Inc. share price today is $24.31 as on August 19, 2026 at 1:29 am IST.

What is the 52 week high and 52 week low of Denali Therapeutics Inc. stock?

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The 52 week high of Denali Therapeutics Inc. stock is $27.27, while the 52 week low is $12.61 as of 19 Aug '26.

What is DNLI's market capitalisation today?

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DNLI market capitalisation is $4.20B as of August 19, 2026, at 11:48 am IST.

What is DNLI's net income for the last quarter?

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DNLI's net income for the last quarter is -0.11B USD.

What is the 5 year returns of DNLI?

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The 5 year returns of DNLI is -54.30% as on 19 Aug '26.

What is the high & low stock price of DNLI today?

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DNLI stock price hit a high of $24.48 and low of $24.01 as of 19 Aug '26.

Can I buy DNLI shares in India?

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Yes. You can buy DNLI in India by opening an international trading account.