US Stocks
/
Upstream Bio, Inc. Share Price
Upstream Bio, Inc. Share Price

Upstream Bio, Inc. Share Price

NASDAQ: UPB | Micro Cap
$5.33
-$0.00 (-0.09%) Last updated on 18 Sep, 2026 | 01:29 IST
  • Performance
  • Chart
  • Fundamentals
  • Quarterly P&L
  • Annual P&L
  • About
  • Price history
  • FAQs

Upstream Bio, Inc. Stock Performance

Open
$5.48
Prev. Close
$5.33
Circuit Range
N/A
Day Range
$5.24 - $5.48
Year Range
$5.24 - $33.58
Volume
31,103
Average Traded
$5.31

Upstream Bio, Inc. Share Price Today

As of 18 September 2026, Upstream Bio, Inc.'s share price is $5.33. The stock opened at $5.48, compared to its previous close of $5.33. During today's trading session, Upstream Bio, Inc.'s share price traded between $5.24 and $5.48, with an average price of $5.36. Over the past 52 weeks, the stock has recorded a high of $33.58 and a low of $5.24. In terms of performance, Upstream Bio, Inc.'s share price has declined by 40.64% over the last six months and is down 71.69% on a year-on-year basis.

Upstream Bio, Inc. Share Price Chart

$5.24$5.48
L
Show Current Price
H

Upstream Bio, Inc. Stock Fundamentals & Key Indicators

Market Cap
$286.77M
PE Ratio (TTM)
-2.00
Dividend Yield
N/A
EPS (TTM)
$-2.66
Revenue (TTM)
$2.85M
Return On Equity (TTM)
-42.22%
Profit Margin
-5026.03%
Debt to Equity
0.04
Quarterly Earnings Growth YoY
-111.03%

Upstream Bio, Inc. Quarterly Profit & Loss

All figures in USD

ParticularsSep 2024Mar 2025Jun 2025Sep 2025
Revenue$607000.00$566000.00$937000.00$683000.00
Net Profit-$15.99M-$27.27M-$39.97M-$33.75M
Net Profit Margin-2634.60%-4818.02%-4265.31%-4941.14%
Income ChangeN/A-70.52%-46.56%15.56%

Upstream Bio, Inc. Annual Profit & Loss

All figures in USD

Particulars20242025
Revenue$2.37M$2.85M
Net Profit-$62.81M-$143.44M
Net Profit Margin-2650.04%-5026.03%
Income ChangeN/A-128.39%

About Upstream Bio, Inc.

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. Its product candidate includes verekitug, which is in Phase 2 clinical development for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps, as well as in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

Upstream Bio, Inc. Historical Returns

MonthOpenCloseChange %
Sep 2026
$6.54
$5.32
-21.65%
Aug 2026
$6.25
$6.79
+7.95%
Jul 2026
$6.95
$6.29
-9.04%
Jun 2026
$8.31
$6.92
-17.24%
May 2026
$9.21
$8.36
-8.89%
Apr 2026
$9.22
$9.17
+2.23%
Mar 2026
$7.58
$8.97
+16.64%
Feb 2026
$31.66
$7.69
-75.25%
Jan 2026
$27.09
$31.07
+14.29%
Dec 2025
$28.32
$27.18
-4.71%
Nov 2025
$25.84
$28.53
+10.41%
Oct 2025
$18.61
$25.84
+37.37%

UPB Share Price FAQs

What is Upstream Bio, Inc. share price today?

chevron-up
Upstream Bio, Inc. share price today is $5.33 as on September 18, 2026 at 1:29 am IST.

What is the 52 week high and 52 week low of Upstream Bio, Inc. stock?

chevron-up
The 52 week high of Upstream Bio, Inc. stock is $33.58, while the 52 week low is $5.24 as of 18 Sep '26.

What is UPB's market capitalisation today?

chevron-up
UPB market capitalisation is $286.77M as of September 18, 2026, at 1:39 pm IST.

What is UPB's net income for the last quarter?

chevron-up
UPB's net income for the last quarter is -0.03B USD.

What is the 5 year returns of UPB?

chevron-up
The 5 year returns of UPB is -78.53% as on 18 Sep '26.

What is the high & low stock price of UPB today?

chevron-up
UPB stock price hit a high of $5.48 and low of $5.24 as of 18 Sep '26.

Can I buy UPB shares in India?

chevron-up
Yes. You can buy UPB in India by opening an international trading account.