Spruce Biosciences, Inc. Share Price
NASDAQ: SPRB | Micro CapSpruce Biosciences, Inc. Stock Performance
Spruce Biosciences, Inc. Share Price Today
As of 30 October 2026, Spruce Biosciences, Inc.'s share price is $46.71. The stock opened at $48.10, compared to its previous close of $47.16. During today's trading session, Spruce Biosciences, Inc.'s share price traded between $46.49 and $48.98, with an average price of $47.74. Over the past 52 weeks, the stock has recorded a high of $127.78 and a low of $38.21. In terms of performance, Spruce Biosciences, Inc.'s share price has declined by 18.00% over the last six months and is down 56.55% on a year-on-year basis.
Spruce Biosciences, Inc. Share Price Chart
Spruce Biosciences, Inc. Quarterly Profit & Loss
All figures in USD
Spruce Biosciences, Inc. Annual Profit & Loss
All figures in USD
About Spruce Biosciences, Inc.
Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enzyme activity. TA-ERT is designed to restore rhNAGLU enzyme activity in the central nervous system following intracerebroventricular injection and promote clearance of heparan sulfate in the brain.
Spruce Biosciences, Inc. Historical Returns
| Month | Open | Close | Change % |
|---|---|---|---|
Oct 2026 | $47.60 | $46.90 | -2.88% |
Sep 2026 | $55.81 | $48.29 | -21.96% |
Aug 2026 | $41.98 | $61.88 | +44.50% |
Jul 2026 | $51.69 | $42.83 | -21.90% |
Jun 2026 | $52.51 | $54.84 | +10.95% |
May 2026 | $58.25 | $49.42 | -13.23% |
Apr 2026 | $68.02 | $56.96 | -11.03% |
Mar 2026 | $53.36 | $64.02 | +8.01% |
Feb 2026 | $80.95 | $59.27 | -28.25% |
Jan 2026 | $83.02 | $82.61 | -2.17% |
Dec 2025 | $96.59 | $84.44 | -14.54% |
Nov 2025 | $107.00 | $98.81 | -8.08% |