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Spruce Biosciences, Inc. Share Price

Spruce Biosciences, Inc. Share Price

NASDAQ: SPRB | Micro Cap
$44.21
-$1.05 (-2.32%) Last updated on 10 Oct, 2026 | 01:29 IST
  • Performance
  • Chart
  • Fundamentals
  • Quarterly P&L
  • Annual P&L
  • About
  • Price history
  • FAQs

Spruce Biosciences, Inc. Stock Performance

Open
$44.84
Prev. Close
$45.26
Circuit Range
N/A
Day Range
$42.90 - $44.84
Year Range
$40.68 - $195.51
Volume
7,247
Average Traded
$43.90

Spruce Biosciences, Inc. Share Price Today

As of 10 October 2026, Spruce Biosciences, Inc.'s share price is $44.21. The stock opened at $44.84, compared to its previous close of $45.26. During today's trading session, Spruce Biosciences, Inc.'s share price traded between $42.90 and $44.84, with an average price of $43.87. Over the past 52 weeks, the stock has recorded a high of $195.51 and a low of $40.68. In terms of performance, Spruce Biosciences, Inc.'s share price has declined by 22.38% over the last six months and is down 58.87% on a year-on-year basis.

Spruce Biosciences, Inc. Share Price Chart

$42.90$44.84
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Show Current Price
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Spruce Biosciences, Inc. Stock Fundamentals & Key Indicators

Market Cap
$33.89M
PE Ratio (TTM)
N/A
Dividend Yield
0.00%
EPS (TTM)
$-17.87
Revenue (TTM)
$0.00
Return On Equity (TTM)
-61.33%
Profit Margin
N/A
Debt to Equity
0.08
Quarterly Earnings Growth YoY
-97.69%

Spruce Biosciences, Inc. Quarterly Profit & Loss

All figures in USD

ParticularsSep 2025Dec 2025Mar 2026Jun 2026
Revenue$0.00$0.00$0.00$0.00
Net Profit-$8.21-$14.65-$12.27-$16.23
Net Profit MarginN/AN/AN/AN/A
Income ChangeN/A-78.44%16.25%-32.27%

Spruce Biosciences, Inc. Annual Profit & Loss

All figures in USD

Particulars2022202320242025
Revenue$0.00$10.09$4.91$0.00
Net Profit-$46.18-$47.92-$53.04-$38.97
Net Profit MarginN/A-474.93%-1080.24%N/A
Income ChangeN/A-3.77%-10.68%26.53%

About Spruce Biosciences, Inc.

Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enzyme activity. TA-ERT is designed to restore rhNAGLU enzyme activity in the central nervous system following intracerebroventricular injection and promote clearance of heparan sulfate in the brain.

Spruce Biosciences, Inc. Historical Returns

MonthOpenCloseChange %
Oct 2026
$47.60
$43.91
-9.07%
Sep 2026
$55.81
$48.29
-21.96%
Aug 2026
$41.98
$61.88
+44.50%
Jul 2026
$51.69
$42.83
-21.90%
Jun 2026
$52.51
$54.84
+10.95%
May 2026
$58.25
$49.42
-13.23%
Apr 2026
$68.02
$56.96
-11.03%
Mar 2026
$53.36
$64.02
+8.01%
Feb 2026
$80.95
$59.27
-28.25%
Jan 2026
$83.02
$82.61
-2.17%
Dec 2025
$96.59
$84.44
-14.54%
Nov 2025
$107.00
$98.81
-8.08%

SPRB Share Price FAQs

What is Spruce Biosciences, Inc. share price today?

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Spruce Biosciences, Inc. share price today is $44.21 as on October 10, 2026 at 1:29 am IST.

What is the 52 week high and 52 week low of Spruce Biosciences, Inc. stock?

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The 52 week high of Spruce Biosciences, Inc. stock is $195.51, while the 52 week low is $40.68 as of 10 Oct '26.

What is SPRB's market capitalisation today?

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SPRB market capitalisation is $33.89M as of October 10, 2026, at 1:06 pm IST.

What is SPRB's net income for the last quarter?

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SPRB's net income for the last quarter is -16.23B USD.

What is the 5 year returns of SPRB?

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The 5 year returns of SPRB is 828.78% as on 10 Oct '26.

What is the high & low stock price of SPRB today?

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SPRB stock price hit a high of $44.84 and low of $42.90 as of 10 Oct '26.

Can I buy SPRB shares in India?

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Yes. You can buy SPRB in India by opening an international trading account.