Ionis Pharmaceuticals, Inc. Share Price

Ionis Pharmaceuticals, Inc. Share Price

NASDAQ: IONS | Mid Cap
$45.58
+$0.66 (1.48%) Last updated on 29 Oct, 2026 | 19:57 IST
  • Performance
  • Chart
  • Fundamentals
  • Quarterly P&L
  • Annual P&L
  • About
  • Price history
  • FAQs

Ionis Pharmaceuticals, Inc. Stock Performance

Open
$45.57
Prev. Close
$44.91
Circuit Range
N/A
Day Range
$45.26 - $45.77
Year Range
$42.18 - $86.71
Volume
17,295
Average Traded
$45.60

Ionis Pharmaceuticals, Inc. Share Price Today

As of 29 October 2026, Ionis Pharmaceuticals, Inc.'s share price is $45.58. The stock opened at $45.57, compared to its previous close of $44.91. During today's trading session, Ionis Pharmaceuticals, Inc.'s share price traded between $45.26 and $45.77, with an average price of $45.51. Over the past 52 weeks, the stock has recorded a high of $86.71 and a low of $42.18. In terms of performance, Ionis Pharmaceuticals, Inc.'s share price has declined by 39.06% over the last six months and is down 38.63% on a year-on-year basis.

Ionis Pharmaceuticals, Inc. Share Price Chart

Line chart of the Ionis Pharmaceuticals, Inc. price trend over the selected period. The price rose overall, ranging from 45.28 to 45.74, ending at 45.58.
$45.26$45.77
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Show Current Price
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Ionis Pharmaceuticals, Inc. Stock Fundamentals & Key Indicators

Market Cap
$7.29B
PE Ratio (TTM)
N/A
Dividend Yield
0.00%
EPS (TTM)
$-3.40
Revenue (TTM)
$943.71B
Return On Equity (TTM)
-128.53%
Profit Margin
-40.41%
Debt to Equity
3.01
Quarterly Earnings Growth YoY
10.85%

Ionis Pharmaceuticals, Inc. Quarterly Profit & Loss

All figures in USD

ParticularsSep 2025Dec 2025Mar 2026Jun 2026
Revenue$156.72$203.33$246.09$267.95
Net Profit-$128.61-$229.39-$92.53-$114.65
Net Profit Margin-82.06%-112.82%-37.60%-42.79%
Income ChangeN/A-78.36%59.66%-23.91%

Ionis Pharmaceuticals, Inc. Annual Profit & Loss

All figures in USD

Particulars2022202320242025
Revenue$587.37$787.65$705.14$943.71
Net Profit-$269.72-$366.29-$453.90-$381.39
Net Profit Margin-45.92%-46.50%-64.37%-40.41%
Income ChangeN/A-35.80%-23.92%15.97%

About Ionis Pharmaceuticals, Inc.

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).

Ionis Pharmaceuticals, Inc. Historical Returns

Share price history by day, with open and close prices and the day's change
MonthOpenCloseChange %
Oct 2026
$44.64
$45.65
+2.17%
Sep 2026
$60.84
$44.68
-28.45%
Aug 2026
$52.63
$62.45
+20.60%
Jul 2026
$79.20
$51.78
-34.74%
Jun 2026
$76.19
$79.34
+3.72%
May 2026
$75.16
$76.50
+2.28%
Apr 2026
$75.50
$74.79
-0.39%
Mar 2026
$79.44
$75.08
-7.45%
Feb 2026
$82.49
$81.12
-1.86%
Jan 2026
$78.99
$82.66
+4.43%
Dec 2025
$82.02
$79.15
-4.36%
Nov 2025
$74.38
$82.75
+11.42%

IONS Share Price FAQs