Trump says Iran ceasefire 'over', rules out further peace talks: 'We have to rid their cancer'

US President Donald Trump declared Wednesday that a ceasefire with Iran was "over as far as I'm concerned," after Tehran launched missiles and drones at US military facilities in Bahrain and Kuwait in retaliation for American strikes and renewed sanctions.

Speaking at the start of a NATO summit in Istanbul, Trump described Iran as "evil, sick people" and "dirty players," accusing Tehran of violating the ceasefire by targeting commercial vessels in the Strait of Hormuz.

"The ceasefire is over as far as I'm concerned," Trump said.

He added that he no longer wanted to negotiate with "this scum," saying the United States was wasting time pursuing diplomacy with Iran.

"It's a waste of time dealing with them," he said, adding that he no longer wanted to deal with "this scum."

"We have to rid their cancer, their cancer," Trump said. "And you know what you do? You've got to cut out cancer early. And that's the way I feel."

His comments appeared to end hopes that Washington would continue pursuing the 60-day diplomatic framework launched last month.

A team led by Vice President JD Vance had been working under a 60-day deadline to secure technical concessions from Tehran aimed at curbing its nuclear ambitions.

The negotiations had progressed slowly and were largely focussed on implementing a memorandum of understanding signed by Trump at the Palace of Versailles on June 17.

The latest exchange has cast fresh doubt over that effort.

Iran launched missiles and drones early Wednesday at US military facilities in Bahrain and Kuwait after American forces struck more than 80 targets across Iran and Washington revoked temporary sanctions relief that had allowed Iranian oil exports under the ceasefire arrangement.

The Islamic Revolutionary Guard Corps said it fired missiles and drones at 85 US military targets in Bahrain and Kuwait. In a statement carried on its Telegram channel, the IRGC said its aerospace and naval forces targeted Bahrain's Salman Port, home to the US Navy's Fifth Fleet, Kuwait's Ali Al Salem Air Base and other American military facilities.

Kuwait's military said its air defenses were responding to "hostile missile and drone threats" and warned residents they could hear explosions as interception systems engaged incoming projectiles.

Bahrain's Interior Ministry said warning sirens had sounded and urged residents to move to the nearest safe place.

The retaliation followed overnight US strikes on more than 80 sites across Iran.

US Central Command said American forces targeted Iranian air defense systems, command-and-control facilities, coastal radar sites, anti-ship missile capabilities and more than 60 Islamic Revolutionary Guard Corps small boats operating in and around the Strait of Hormuz.

The strikes were intended to "degrade Iran's ability to continue attacking international commerce flowing through the international trade corridor," CENTCOM said.

Washington said the operation was launched after Iran attacked three commercial vessels transiting the Strait of Hormuz despite the ceasefire.

"Iran's demonstrated aggression was unwarranted, dangerous, and a clear violation of the ceasefire," CENTCOM said, adding that US forces remained prepared to hold Iran accountable if it failed to comply with the agreement.